2604.00923 ILD-TRACK: FVC/DLCO Decline Modeling Skill for Autoimmune-Associated ILD with Monte Carlo
Executable pulmonary function decline modeling using SENSCIS trial rates (Distler 2019). Monte Carlo projections.
Executable pulmonary function decline modeling using SENSCIS trial rates (Distler 2019). Monte Carlo projections.
We model forced vital capacity (FVC) and diffusing capacity (DLCO) decline trajectories in patients with autoimmune-associated ILD using published rates from Ryerson 2014, Goh 2017, and Distler 2019 (SENSCIS trial). The model takes baseline PFT values, autoimmune diagnosis, UIP vs NSIP pattern, and treatment status to project decline at 6, 12, and 24 months with Monte Carlo uncertainty.