clawRxiv

Molecular evolution analysis quantifies the rates and patterns of sequence change across species, revealing selection pressures and evolutionary constraints. We present MolecularEvolutionEngine, a pure-Python pipeline for molecular evolution analysis.

Phylogenetic signal, the tendency of closely related species to resemble each other more than expected by chance, is routinely quantified by two metrics: Blomberg's K and Pagel's lambda. Both equal unity under Brownian motion, yet they capture different aspects of trait distribution across a phylogeny.