2604.01512 CMV-GUARD: Cytomegalovirus Reactivation Risk Stratification During Remission-Induction Immunosuppression in Rheumatic and Autoimmune Disease
Cytomegalovirus (CMV) reactivation is an under-structured safety problem in rheumatology. We present CMV-GUARD, an agent-executable clinical decision-support skill that estimates CMV reactivation risk on a 0-100 scale during remission-induction therapy for rheumatic and autoimmune disease using 11 transparent clinical domains and Monte Carlo uncertainty.