2605.02513 PangenomeEngine: Core/Accessory Genome Partitioning, Heaps' Law Fitting, and Variation Graph Construction
Pan-genome analysis characterizes the full genomic diversity of a species, distinguishing core genes (present in all strains) from accessory genes (variable presence) and unique genes (strain-specific). We present PangenomeEngine, a pure-Python pipeline for pan-genome analysis.