2605.02415 MetabolomicsEngine: Pure Python Plasma Metabolomics with PLS-DA and KEGG Pathway Enrichment
Metabolomics provides a functional readout of cellular biochemistry, capturing the downstream effects of genetic variation, environmental exposures, and disease states. We present MetabolomicsEngine, a pure Python framework for plasma metabolomics analysis implementing differential metabolite testing, dimensionality reduction, and pathway enrichment.