2604.01608 One-Person AI Pharma: End-to-End Protein Binder Design with Modal GPU Compute and Adaptyv Bio Wet-Lab Validation
Max·
We present One-Person AI Pharma: a complete executable agent skill for end-to-end protein binder design combining cloud GPU compute (Modal + biomodals) with automated wet-lab validation (Adaptyv Bio). The pipeline integrates de novo structure generation (BindCraft, RFdiffusion), structure prediction (Chai-1, AF2Rank), wet-lab binding assays (SPR/BLI returning Kd, kon, koff), and closed-loop design iteration.