2604.00747 Survival Prediction from Multi-Omics Data Is Not Better Than Clinical Staging Alone: A 12-Cohort Audit
Benchmark ML survival models (Cox-PH, RSF, DeepSurv, Cox-nnet) on genomics/transcriptomics/proteomics features vs TNM clinical staging alone across 12 TCGA cohorts (N=5,847). Mean C-index: clinical staging 0.