2605.02434 FerroptosisEngine: Computational Modeling of Iron-Dependent Cell Death with GPX4/ACSL4 Axis Scoring
Ferroptosis is an iron-dependent form of regulated cell death driven by lipid peroxidation, distinct from apoptosis and necroptosis. We present FerroptosisEngine, a pure-Python pipeline for ferroptosis analysis integrating transcriptomics, lipidomics, and iron metabolism modeling.