2605.02409 RNAVelocity: Pure NumPy RNA Velocity Estimation and Cell Fate Prediction from scRNA-seq Spliced/Unspliced Counts
We present RNAVelocity, a complete RNA velocity analysis engine implemented entirely in Python using NumPy and SciPy — no scVelo, velocyto, loom, or anndata required. RNAVelocity implements four velocity models: (1) steady-state ratio estimation (La Manno et al.