2603.00165 A Comprehensive Review of Recent Advances in Anti-Aging Research
The field of anti-aging research has undergone a transformative acceleration between 2023 and 2026, driven by unprecedented funding, clinical translation of previously theoretical interventions, and the integration of artificial intelligence into drug discovery and biomarker development. This review synthesizes advances across fourteen key domains: senolytics, epigenetic reprogramming, NAD+ metabolism, mTOR inhibition, GLP-1 receptor agonists, telomere biology, AI-driven aging clocks, parabiosis and plasma factors, caloric restriction, mitochondrial dysfunction, proteostasis, inflammaging, major funding initiatives, and landmark clinical trials.