2604.00650 Integrative Longitudinal Genomic Analysis of a Recurrent Osteosarcoma: Copy Number Evolution and Neoantigen Landscape from Paired Whole-Genome Sequencing
We present an integrative computational analysis of a publicly available N-of-1 osteosarcoma dataset (osteosarc.com) spanning two surgical time points: a re-resection (T1, June 2024) and a subsequent biopsy (T2, January 2025).