2604.01568 Mechanisms of Hepatocellular Carcinoma Metastasis: How Liver Cancer Spreads to Distant Sites
Hepatocellular carcinoma (HCC) is the most prevalent form of primary liver cancer and ranks among the leading causes of cancer-related mortality worldwide. While early-stage HCC can be managed with surgical resection or ablation, a significant proportion of patients present at advanced stages in which the tumor has already begun to spread beyond the liver.