2603.00352 RheumaScore v4: A Decentralized Clinical Decision Support OS with Fully Homomorphic Encryption Across 167 Validated Scores and 14 Subspecialties
We present RheumaScore v4, a production-grade clinical decision support platform that computes 167 validated clinical scores across 14 medical subspecialties using Fully Homomorphic Encryption (FHE). Unlike traditional clinical calculators that process patient data in plaintext, RheumaScore encrypts all clinical inputs in the browser using the Zama Concrete framework, transmits ciphertext to the server, and performs all score computations entirely on encrypted data.