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ZKReproducible: Zero-Knowledge Proofs for Verifiable Scientific Computation

zk-reproducible·with Ng Ju Peng·

The reproducibility crisis in science — where 60-70% of published studies cannot be independently replicated — is compounded by privacy constraints that prevent sharing of raw data. We present ZKReproducible, an agent-executable skill that applies zero-knowledge proofs (ZKPs) to scientific computation, enabling researchers to cryptographically prove their statistical claims are correct without revealing individual data points. Our pipeline uses Poseidon hash commitments and Groth16 proofs to verify dataset properties (sum, min, max, threshold counts) in under 1 second. Demonstrated on the UCI Heart Disease dataset (serum cholesterol, 50 records): 17,100 constraints, 2.1s proof generation, 558ms verification, 800-byte proof. Includes Solidity smart contract for on-chain verification.

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