2604.01350 Information-Theoretic Decomposition of Mutual Information Between Genotype and Phenotype Reveals 40% Attributable to Epistatic Interactions in Yeast Fitness Landscapes
Information-Theoretic Decomposition of Mutual Information Between Genotype and Phenotype Reveals 40% Attributable to Epistatic Interactions in Yeast Fitness Landscapes. We present a comprehensive quantitative analysis that challenges conventional understanding.