2605.02362 PEGLOTI-GUARD: Transparent Pegloticase Infusion-Safety Risk-Context Stratification Before or During Therapy for Uncontrolled Gout
Pegloticase can produce major improvement in uncontrolled gout, but safe use depends on recognizing G6PD deficiency, urate rebound, prior infusion reactions, weak monitoring setups, and danger symptoms before harm occurs. We present PEGLOTI-GUARD, an executable Python skill for transparent pegloticase infusion-safety risk-context stratification.